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Deepak Lokwani - India

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About Deepak Lokwani

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Deepak Lokwani is currently living in India, and is interested in Computer Hardware, Education, Work from Home.
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Location

India

Categories of Interest

Computer Hardware, Education, Work from Home

Resume

To,
The Manager,
Human Resource Development


Subject: - Application for the suitable post in your esteemed organization.


Dear Sir or Madam,
My Name is Deepak K. Lokwani and I recently completed M. Pharm from AISSMS College of Pharmacy, Pune. I would like to forward my candidature for the suitable post in your esteemed organization. Please find my resume annexed herewith for your kind perusal.

During My academic pursuits, I frequently had the opportunity to utilize my skills, abilities, and I attained a high degree of proficiency in handling of Molecular modeling softwares. I also have a proven my abilities in synthesis and biological screening of new compounds for anticancer activity during my entire research project.

I am now desperate to pragmatically explore the conceptual assets gained through my graduation & post graduation for the Research and Development and Drug Discovery process. With My solid knowledge base, enthusiasm for learning, and superior work habits, I am certain that I could be a powerful contributor to your organization.

Thanking you for taking your time to review my qualification. I am anticipating your positive reply if there is opening suitable for my profile. Kindly oblige and consider my application favorably
Thanking you.


Sincerely Yours,
Deepak K. Lokwani
M. Pharm.
(Pharmaceutical Chemistry)
E-mail: dklokwani@gmail.com
Mobile No. : +91-9372593591

Deepak K. Lokwani
Present Address: Permanent Address:
C/o Jayant Barve S/o. Khatumal V. Lokwani
32, Mangalwadi, Nanak Nager, Nimwadi
Senapati Bapat Road, Pune Camp, Akola
Maharashtra-411011 Maharashtra-444001
Mob. 9372593591 Contact No. (0724) 2426001
Email ID: dklokwani@gmail.com


Objective:
To work with an organization of distinction in Pharmacy sector which recognizes my true potential and provides me sufficient avenues for professional growth through nurturing my skills and competencies

Areas of Interest:
Research and Development
Development of Selective Therapeutic Agents
Computer-Aided Drug Design
Intellectual Property Rights & Drug Regulatory Affairs

Profile and Strength:
A young and dynamic individual with a strong academic background recently published a research article in European Journal of Medicinal Chemistry.

Successfully qualified GATE 2007 conducted by Indian Institute of Technology (IIT), Kanpur with 94.08 Percentile (AIR 1079, GATE Score 413).

Received Junior Research Fellowship (2007-2009) by Govt. of India, Ministry of Human Resource development (MHRD) GATE-Scholarship for two years from 2007-2009.

Multilingual with proficiency in English, Hindi and Marathi.






Academic Credentials:

EXAM INSTITUTION BOARD/
UNIVERSITY YEAR RESULT
M. Pharm. II nd year
(Pharmaceutical Chemistry) AISSMS College of Pharmacy, Pune University of Pune
2009 Result Awaited
M. Pharm. I st year
(Pharmaceutical Chemistry) AISSMS College of Pharmacy, Pune University of Pune
2008 60.77%
B. Pharm. S.N.I.O.P. Pusad Amravati University
2007 64.83%
D. Pharm.
G.K.I.P. Akola

MSBTE 2004 74.50%
H.S.C. Akola Arts, Commerce and Science Jr. College, Akola

Amravati 2002 65.17%
S.S.C Guru Nanak Vidyalaya, Akola
Amravati 2000 63.60%

Dissertation Project Undertaken:
Title:
Development of selective Antineoplastic agents using Molecular modeling Studies

Abstract: -
Quantitative StructureActivity Relationship (QSAR) studies have been successfully applied for correlating chemical structures and biological activities of natural and synthetic chemicals. In current work, 2D and 3D QSAR studies have been carried out for establishing a correlation between the structural properties of Benzyl Urea derivatives and their antitumor activities. From this correlation, the New Chemical Entities (NCEs) were designed and the binding affinity of designed compounds was studied on Epidermal Growth Factor Receptor (EGFR) using docking studies and predicted ADMET properties. Finally the most promising compounds from these screening were synthesized and biologically evaluated for their anticancer properties. Compound 1-(2, 4-dimethylphenyl)-3, 3-dimethyl-1-(2-nitrobenzyl) urea (DL-4) showed significant antiproliferative activity ( at 100 ug/ml ) in human cancer cell lines-T-cell leukemia (Jurkat J6), Myelogenous leukemia (K562) and Breast cancer (MCF-7) compared to reference standard 5-Flurouracil.
Publication and Presentations:

Presented a poster entitled Pharmacophore Optimization of selective protein kinase inhibitors using Molecular modeling studies at 60th Indian Pharmaceutical Congress 2008, Delhi.

Co-author in Poster presentation entitled Design and synthesis of novel anticancer agent using molecular modeling techniques in Innovation 2008, at S.G.R.S. College of Pharmacy, Saswad Pune.

Research article accepted in European journal of Medicinal Chemistry entitled Design, Synthesis and Pharmacological Screening of Novel Nitric Oxide Donors Containing1, 5-Diaryl Pyrazolin-3-One as Non Toxic NSAIDs. (Available online as Article in Press), http://dx.doi.org/10.1016/j.ejmech.2009.06.035

Prepared a research article communicated to Journal of Enzyme Inhibition and Medicinal Chemistry entitled Design, Synthesis and Evaluation of Anti-inflammatory, Analgesic, Ulcerogenicity and Nitric oxide releasing studies of Novel Indomethacin analogs as Nonulcerogenic Derivatives.

Prepared a research article communicated to Bioorganic and Medicinal Chemistry entitled Use of Quantitative Structure Activity Relationship (QSAR), Docking and ADMET Prediction Studies as Screening Methods for design of Benzyl Urea Derivatives for Anticancer Activity.

Prepared a research article communicated to Medicinal Chemistry Research entitled Design, Docking Study and ADME prediction of Isatin Derivatives as Anti-HIV Agents.


Computer and Technical Proficiencies:

 Drug Design Software:
 Well Conversant with handling of QSAR and Molecular Modeling Softwares like
Glide 5.0, Qikprop 3.1, Strike 1.7, Sitemap 2.2 by Schrodinger Inc. USA
Discovery Studio 2.1 by Accelrys, USA
Molecular Design Suite 3.5 by Vlife Sciences, Pune, India
Molegro Vertual Docker 2008, Denmark
q-Tox, q- ADME, q-hERG, q-Albumin by Quantum Lead, Russia
TSAR 3.3 by Oxford Molecular Ltd, Accelrys, USA
Chemoffice 2004 and 2008, CambridgeSoft



 Familiar with of Drug Design softwares like
Autodock 3.0.5, USA
FlexX 3.1, Germany
LigandScout 2.0, Austria/Europe
Swiss PdbViewer 4.0.1, Switzerland

 Analytical instrument, Handling Experience: -
UV-Visible Spectrophotometer- JASCO V-530, Japan
FTIR Instrument-JASCO 460 Plus, Japan
Microwave Synthesis Station- Catalyst, Pune, India


Additional information:

Date of Birth : December 31, 1984

Languages Known : Hindi, English and Marathi

References : Dr. Padma Shastri,
Scientist G,
National Centre for Cell Science (NCCS), Pune
Phone No. 09423004092

Mr. S. V. Bhandari
Assistant Professor (Pharmaceutical Chemistry)
AISSMS College of Pharmacy, Pune
Phone No. 09423574082

Quick Profile Summary

Deepak Lokwani
Name: Deepak Lokwani
Link: http://www.salespider.com/p-7413853/deepak-lokwani
Location: India

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