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Cytokines play a pivotal role in regulating a variety of immune responses mainly by downstream gene activation or repression. To transduce extracellular signals into intracellular responses, many cytokines utilize a common pathway - the Janus kinase (Jak)-signal transducer and activator of transcription (STAT) signaling pathway. Jak-STAT signaling pathway was first discovered through the study of gene activation in response to type I and II interferons (IFNs).
June 29, 2016
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45-1 Ramsey Road, Shirley, NY 11967, USA, Shirley, New York
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www.creativebiomart.net/researcharea-jak-stat-signaling-proteins_448.htm
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Jak proteins